Since 1985 Prof Dr. Ruitenberg developed 4-years curriculum in order to harmonize international education requirements, recognition and registration of this profession. The commission registration laboratory animal pathologists was then established. In 1990 this initiative was further expanded by Prof. Dr. J Vos in 1990 in cooperation with the former committee members. Currently the education has two directions, with the final purpose registration as laboratory Animal Pathologist (consider pathology reseach in animal models of human deseases), or Toxicologic Pathologist. The education curriculum for Toxicologic Pathologists is internationally considered to be one of the better educations for the profession (Version Curriculum1996: “Regulations on Education and Registration/Training programme, Committee for the registration of laboratory Animal/Toxicological Pathologists (CRP/TP) in The Netherlands”).

Currently, every 5 years the Committee for the registration of laboratory Animal/Toxicological Pathologists (CRP/TP) checks the registration status of all Board Certified Pathologists for re-registration. Re-registration will occur every 5 years and will be approved if the Toxicologic Pathologist has remained active in the field during these 5 years. Requirements for approval besides the daily activities within the field (can also include management activity in the pathology field) are courses, post-academic education, slide seminars, congresses and other meetings, publications or presentations.

Dr. R.J.M.M. Thoolen was Board Certified since 1993. On June 15th, 2022 he received his re-registration as Toxicologic Pathologist for the next 5 years.


Ukraine is under attack just to feed "the Ego" of some. It is time that they gain insight into the "non-sense" of war. In this turmoil, Global Pathology Support (GPS) is ploughing on to guard the safety of vaccines, medicines, and chemicals. We just finished full read evaluations of two large projects on carcinogenicity (OECD 453) and histopathology and neuropathology evaluations of one extended one generation toxicity/neurotoxicity study (OECD 443).

A chapter on liver, gallbladder, and pancreas for CRC Press/Francis-Taylor Publishers to publish in a book titled “Toxicologic Pathology: An Atlas “has been finished recently and which will be published in 2022.

GPS is also considering applying Digital Pathology, as recent developments in this area has opened doors, for not only peer review or educational pathology, but also for routine histopathology evaluations. Many publications have shown reliable assessment for different organs systems as compared to conventional (toxicologic) pathology. At the same time pragmatic gain has been established over the years in the speed, logistics and resolution of images generated by digital scanning. Many good systems are on the market like: Hamamatsu, 3DHistech, Aperio (Leica), Sectra and last but not least Phillips. Quality, inter-activity and flexibility are paramount for GPS for the use of such system as it has to match the conventional pathology assessment as close as possible in every aspect and meet the GLP-guidelines.

Other services by GPS to our clients that has already been implemented, is the histology preparation of slides from wet tissues in combination with histopathology evaluation.

Keeping up the good spirit for everyone around the world for a better and safer world, GPS keeps on contributing to our clients in the best possible ways in order to produce safe vaccines, pharmaceuticals and chemicals on a global scale.

For more information call +31 70 3142404.

Kind regards,
Dr. Bob

Following the announcement of 02 September, 2021, I am pleased to announce that we have again gained our new GLP-Compliance from the Dutch Authorities.



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